IMPACT is the UK’s first ever clinical trials partnership dedicated to improving the outcomes of stem cell transplant patients.
A stem cell transplant is a potential cure for patients with a blood cancer or blood disorder, but there is an urgent need to improve patient outcomes. Of those who receive stem cells from an unrelated donor, fewer than half will reach the milestone of five-year survival.
This much-needed improvement in patient outcomes can only be achieved through research. Clinical trials are crucial in forming the evidence base for new approaches to treatment.
Improving patient outcomes
By providing the vital infrastructure that transplant centres need to work together, IMPACT will make it easier and quicker to deliver clinical trials that focus on improving stem cell transplant outcomes. As a result of this UK-wide partnership, IMPACT trials will reach a much larger patient population than would be possible at an individual transplant centre. There are dedicated IMPACT research nurses in ten centres, plus a further twelve affiliated centres which also participate in clinical trials.
Funders
IMPACT is a partnership of organisations committed to improving the outcomes of stem cell transplantation through cutting-edge research. It is jointly funded by Anthony Nolan, Leukaemia UK and NHS Blood and Transplant.
Partners
IMPACT is delivered in partnership with the British Society of Blood and Marrow Transplantation (BSBMT) and the Cancer Research UK Clinical Trials Unit (CRCTU) at the University of Birmingham.
Transplant Centres
There are IMPACT research nurses in eleven centres, plus a further eleven affiliated centres which also participate in clinical trials.
Transplant Centre | Location | Principal Investigator |
---|---|---|
Addenbrooke's Hospital | Cambridge | Dr Charles Crawley |
Beatson West of Scotland Cancer Centre | Glasgow | Dr Anne Parker |
Churchill Hospital | Oxford | Dr Andy Peniket |
Freeman Hospital | Newcastle | Professor Matthew Collin |
King’s College Hospital | London | Dr Victoria Potter |
Manchester Royal Infirmary | Manchester | Dr Eleni Tholouli |
Queen Elizabeth Hospital | Birmingham | Professor Charlie Craddock |
St James's University Hospital | Leeds | Dr Jennifer Clay |
University College London Hospitals | London | Dr Kavita Raj |
University Hospital of Wales | Cardiff | Dr Keith Wilson |
University Hospitals Bristol | Bristol | Dr Rachel Protheroe |
Transplant Centre | Location | Principal Investigator |
---|---|---|
The Christie | Manchester | Dr Adrian Bloor |
Derriford Hospital | Plymouth | Dr Hannah Hunter |
Hammersmith Hospital | London | Dr Eduardo Olavarria |
Heart of England | Birmingham | Dr Emmanuel Nikolousis |
Leicester Royal Infirmary | Leicester | Dr Murray Martin |
Nottingham City Hospital | Nottingham | Dr Jenny Byrne |
Royal Hallamshire Hospital | Sheffield | Professor John Snowden |
Clatterbridge Cancer Centre | Liverpool | Dr Yngvar Floisand |
The Royal Marsden Hospital | London | Dr Sandra Easdale |
Southampton General Hospital | Southampton | Dr Kim Orchard |
St Bartholomew's Hospital | London | Dr Jeff Davies |